mantispy.ds.depmap_expression#

mantispy.ds.depmap_expression(cache_dir=None)[source]#

Path to the DepMap expression matrix, fetched from DepMap’s public release on first use.

The file is OmicsExpressionProteinCodingGenesTPMLogp1.csv from DepMap Public 24Q2: one row per model, gene columns named "SYMBOL (ENTREZ)", holding log2(TPM+1). It is the reference unexpressed_genes() and correct_chromosome_arm() read the genes a cell line does not express from. The download is checked against a pinned checksum.

Parameters:
cache_dir str | Path | None (default: None)

Where to keep the download. Defaults to mantispy.settings.cache_dir.

Return type:

Path

Returns:

The path of the cached CSV file.

Notes

DepMap data is distributed by the Broad Institute under CC BY 4.0; it is fetched from DepMap’s own figshare release, not re-hosted.